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Can You Take CBD With Vitamins? All You Need To Know

March 9, 2021
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can you take cbd with vitamins

CBD is spreading like wildfire leading healthy consumers who take daily vitamins to wonder if it’s safe to mix both CBD and vitamins.

CBD in its pure form does not appear to interact with vitamins. Additives in your CBD product might affect the uptake and processing of vitamins. Yet, the science of CBD is emerging, implying the need for research. To ensure your safety, always check with your doctor before starting or mixing CBD. 

To make an informed decision, you might want to read what’s coming up, so let’s dive right in and find out if you can take CBD with vitamins!

Can You Take CBD Oil And Vitamins Together?

While CBD oil and vitamins do not seem to interfere with each other, there might be positive effects on the simultaneous consumption. 

As with every supplement, both vitamins and CBD should be consumed in a moderate amount under the guidance of a healthcare professional.

Since vitamins are organic compounds that cannot be produced by the human body, some people may require additional nutrients taken in the form of supplements.

Just like vitamins, cannabinoids such as CBD are an essential nutrient and also cannot be produced inside our body.

What makes CBD an essential nutrient is that cannabinoids have been found to support normal appetite, sleep, and other aspects of life as it is involved in proper function of the Endocannabinoid System (ECS).

CBD is a phytonutrient extracted from plants operating through complex interactions with your body’s ECS via indirect stimulation of cannabinoid receptors located on nearly every cell of the human body.

With over 700 clinical trials in various stages of progression, research into the benefits of CBD continues to expand in our understanding with ongoing verification by scientific communities around the world.


Does CBD Interact With Vitamins?

Current observations and anecdotal reports are showing no negative interactions between CBD and vitamins.

Even though CBD is only one molecule in most CBD oil products, most CBD products contain a variety of vitamins and amino acids — depending on the carrier oil and other potential ingredients. 

While CBD may not negatively interact with vitamins, CBD may operate and interact in a complementary fashion to your routine daily vitamin intake. 

A potential complementary interaction between CBD and your daily vitamins occurs by making its way to be metabolized in the liver through specific processes. 

Once CBD and other vitamin molecules reach the liver, certain enzymes known as CYP450 will break it down via complex mechanisms. 

Your liver’s primary job, when operating in a normal peak healthy state, takes the various molecules and breaks them down using specific mechanisms as part of the normal routine digestive process.

As your liver is processing the CBD, vitamin, and other potential drug molecules, the enzyme breaking things down may either cause an upregulation or downregulation.

This up or down regulation by your liver may cause CBD, vitamins, and other molecules to get processed by your liver more quickly or more slowly.

A faster or slower processing by your liver may lead to an increase in potential side effects.

Before mixing CBD, vitamins, and other drug molecules, caution is recommended along with a quick chat with your family physician or primary healthcare provider. 

Can You Take CBD Oil And Multivitamins Together?

With ongoing research continuing to pick up the pace, only your healthcare physician should recommend you take cannabidiol and multivitamins together. 

One potential reason for taking CBD with multivitamins is to optimize how multivitamins are balanced and distributed throughout the body.

CBD and multivitamins can provide important nutrients for those lacking a well rounded and balanced diet. 

Specific benefits of multivitamins and CBD include boosting the immune system by acting as coenzymes in the catalysis of biological reactions and fluidify the digestive tract.

Of course, multivitamins and CBD are not expected to replace a balanced diet, instead, they are meant to reinforce a proper diet.

CBD oil specifically on the other hand provides balance and optimization of the body’s homeostasis using chemical communication mechanisms to achieve balance throughout the body.

According to cannabis expert, Dr. David Allen, homeostasis is your body’s ability to stay away from death.

If anything in your system gets too high or too low, without the ECS balancing the homeostatic processes between your body’s vital systems, death is more likely.

For now, the benefits of CBD and multivitamins seem to be distinct and tend to attract those searching for holistic health improvement.

Can You Take CBD Oil With Vitamin D?

No evidence exists suggesting a negative interaction between Vitamin D and CBD. 

While CBD isolate does not necessarily contain Vitamin D, CBD using hemp oil carrier might contain Vitamin D3 in a sufficient dietary amount. 

Some research shows that CBD oil might reduce the effectiveness of vitamin D in calcium absorption, without leading to side effects. 

Further research continues showing CBD in combination with vitamin D3 facilitates the normal regeneration of bone tissue and the differentiation of mesenchymal stem cells in dental tissue.

Vitamin D is an important vitamin coming from dietary sources as well as sunlight. 

Since most people don’t get enough vitamin D from sunlight, they are sometimes required to take additional food supplements. 

By taking CBD and Vitamin D together, the effects can contribute to normal bone growth and normal bone function. 

With Vitamin D also able to help your body absorb calcium, together with CBD, the revitalizing effects can help maintain normal strong bones.

As a safety net, it’s always recommended you consult your family doctor before adding CBD to your medication routine. 

Can You Take CBD Oil With Vitamin C?

According to, CBD is “not” one of the 27 known minor and moderate drug interactions that vitamin C can have with certain medications.

Depending on the carrier oil (and other potential ingredients) used in your CBD products, CBD in a hemp seed carrier oil may contain some vitamin C.

With hemp seed oil as a popular carrier oil, it should be safe for those who are able to take vitamin C in the form of hemp oil.

If you’re aiming to take CBD and eat citrus fruit (as your source of vitamin C) together, there could be various complementary desirable benefits. 

Vitamin C is found in citrus fruits such as oranges, lemons, limes, grapefruit, and more.

Even though not all citrus are created equal, eating grapefruit with CBD might require a bit of caution for specific reasons. 

Grapefruit has a bit of a history of inhibiting certain enzymes that can alter the way molecules, such as CBD, interact with your body — such as increasing the potency of CBD and/or slowing down the processing of CBD.

The specific enzyme responsible for potentially interfering with CBD is the CYP3A4, from the CYP450 family. 

While grapefruit interacting with CBD might not be necessarily a bad thing, you may have to alter your current dosage. 

Since CBD has a high safety profile and only a few mild side effects, taking grapefruit together with CBD can increase the side effects. 

Even though this interaction is not caused by the vitamins contained in the grapefruit, it’s something to be aware of and consider before taking CBD or any other medication or citrus fruits. 

Before self-administration of any substance, even CBD isolate, you should seek advice from your family physician first.


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